Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50221985 (CHEMBL241010 | H-Dmt-Tic-NH-CH2-CH2-NH2) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.72 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Ferrara Curated by ChEMBL | Assay Description Displacement of [3H]DAMGO from mu-opioid receptor in Sprague-Dawley rat brain P2 synaptosome membrane | Bioorg Med Chem 15: 6876-81 (2007) Article DOI: 10.1016/j.bmc.2007.08.047 BindingDB Entry DOI: 10.7270/Q2XD11D9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (GUINEA PIG) | BDBM50221985 (CHEMBL241010 | H-Dmt-Tic-NH-CH2-CH2-NH2) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 286 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Ferrara Curated by ChEMBL | Assay Description Agonist activity at mu-opioid receptor in Hartley guinea pig ileum assessed as inhibition of electrically-stimulated muscle contraction | Bioorg Med Chem 15: 6876-81 (2007) Article DOI: 10.1016/j.bmc.2007.08.047 BindingDB Entry DOI: 10.7270/Q2XD11D9 | |||||||||||
More data for this Ligand-Target Pair |