Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM50297506 (CHEMBL551074 | l7-(cyclopropylmethyl)-3,l4-dihydro...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of New England Curated by ChEMBL | Assay Description Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells by liquid scintillation counting | Bioorg Med Chem Lett 19: 2811-4 (2009) Article DOI: 10.1016/j.bmcl.2009.03.095 BindingDB Entry DOI: 10.7270/Q29G5MW7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM50297506 (CHEMBL551074 | l7-(cyclopropylmethyl)-3,l4-dihydro...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of New England Curated by ChEMBL | Assay Description Binding affinity to mu opioid receptor | Bioorg Med Chem Lett 22: 6801-5 (2012) Article DOI: 10.1016/j.bmcl.2012.06.056 BindingDB Entry DOI: 10.7270/Q28G8MSQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM50297506 (CHEMBL551074 | l7-(cyclopropylmethyl)-3,l4-dihydro...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a |
University of New England Curated by ChEMBL | Assay Description Inverse agonist activity at human recombinant mu opioid receptor expressed in CHO cells after 3 hrs by [35S]GTPgammaS binding assay | Bioorg Med Chem Lett 22: 6801-5 (2012) Article DOI: 10.1016/j.bmcl.2012.06.056 BindingDB Entry DOI: 10.7270/Q28G8MSQ | |||||||||||
More data for this Ligand-Target Pair |