Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM50535351'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50535351 (CHEMBL4459271) Show SMILES OC(=O)C(F)(F)F.Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@@H]1CCN(c2ccc(Cc3cc4ccccc4o3)cc12)S(C)(=O)=O |r| Show InChI InChI=1S/C30H33N3O5S.C2HF3O2/c1-18-12-22(34)13-19(2)24(18)17-26(31)30(35)32-27-10-11-33(39(3,36)37)28-9-8-20(15-25(27)28)14-23-16-21-6-4-5-7-29(21)38-23;3-2(4,5)1(6)7/h4-9,12-13,15-16,26-27,34H,10-11,14,17,31H2,1-3H3,(H,32,35);(H,6,7)/t26-,27+;/m0./s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cell membranes measured after 1 hr by liquid scintillation counting...				J Med Chem 62: 4193-4203 (2019) Article DOI: 10.1021/acs.jmedchem.9b00378 BindingDB Entry DOI: 10.7270/Q2542S2Q
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50535351 (CHEMBL4459271) Show SMILES OC(=O)C(F)(F)F.Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@@H]1CCN(c2ccc(Cc3cc4ccccc4o3)cc12)S(C)(=O)=O |r| Show InChI InChI=1S/C30H33N3O5S.C2HF3O2/c1-18-12-22(34)13-19(2)24(18)17-26(31)30(35)32-27-10-11-33(39(3,36)37)28-9-8-20(15-25(27)28)14-23-16-21-6-4-5-7-29(21)38-23;3-2(4,5)1(6)7/h4-9,12-13,15-16,26-27,34H,10-11,14,17,31H2,1-3H3,(H,32,35);(H,6,7)/t26-,27+;/m0./s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.340	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity at rat mu opioid receptor expressed in rat C6 cell membranes assessed as stimulation of [35S]GTPgammaS binding measured after 1 hr				J Med Chem 62: 4193-4203 (2019) Article DOI: 10.1021/acs.jmedchem.9b00378 BindingDB Entry DOI: 10.7270/Q2542S2Q
					More data for this Ligand-Target Pair