Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50548320 (CHEMBL4754944) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.950 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of [3H]DAMGO from mu opioid receptor in rat brain membranes incubated for 45 mins by liquid scintillation counting method | Citation and Details Article DOI: 10.1021/acs.jmedchem.8b01327 BindingDB Entry DOI: 10.7270/Q2RB7870 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM50548320 (CHEMBL4754944) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 0.380 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at human MOR expressed in CHO cell membranes incubated for 60 mins scintillation counting assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.8b01327 BindingDB Entry DOI: 10.7270/Q2RB7870 | |||||||||||
More data for this Ligand-Target Pair |