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Found 1 hit Enz. Inhib. hit(s) with Target = 'Multidrug resistance-associated protein 1' and Ligand = 'BDBM50363089'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Multidrug resistance-associated protein 1


(Homo sapiens (Human))		BDBM50363089
PNG
(CHEMBL1945304)
Show SMILES COc1cc(cc(OC)c1OC)C(=O)Nc1ccc(cc1[N+]([O-])=O)-c1cccnc1
Show InChI InChI=1S/C21H19N3O6/c1-28-18-10-15(11-19(29-2)20(18)30-3)21(25)23-16-7-6-13(9-17(16)24(26)27)14-5-4-8-22-12-14/h4-12H,1-3H3,(H,23,25)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 6.10E+3n/an/an/an/an/an/a



Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL


Assay Description
Inhibition of MRP1 expressed in MDCK cells assessed as calcein AM accumulation after 30 mins by fluorescence assay

J Med Chem 55: 424-36 (2012)


Article DOI: 10.1021/jm201305y
BindingDB Entry DOI: 10.7270/Q2HD7W35
More data for this
Ligand-Target Pair