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Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M1' and Ligand = 'BDBM50119638'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50119638
PNG
(CHEMBL3618448)
Show SMILES CN(CCc1ccc(F)cc1)C(\C)=N\c1ccc2C[C@@H](O)[C@H](NC(=O)c3ccc(Br)cc3)c2c1 |r|
Show InChI InChI=1S/C27H27BrFN3O2/c1-17(32(2)14-13-18-3-10-22(29)11-4-18)30-23-12-7-20-15-25(33)26(24(20)16-23)31-27(34)19-5-8-21(28)9-6-19/h3-12,16,25-26,33H,13-15H2,1-2H3,(H,31,34)/b30-17+/t25-,26-/m1/s1
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n/an/an/an/a 81n/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human muscarinic M1 receptor expressed in CHO cells after 30 mins by GTPgamma35S binding assay

Bioorg Med Chem Lett 25: 4158-63 (2015)


Article DOI: 10.1016/j.bmcl.2015.08.011
BindingDB Entry DOI: 10.7270/Q2GM8938
More data for this
Ligand-Target Pair