Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M1' and Ligand = 'BDBM50135205'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50135205 (CHEMBL3745855) Show SMILES OC[C@H]1CC[C@@H](CC1)NC(=O)c1cn(Cc2ccc(cc2)-n2cccn2)c2cccnc12 |r,wU:5.8,wD:2.1,(6.87,9.12,;5.66,8.87,;5.18,7.41,;3.68,7.09,;3.2,5.62,;4.23,4.48,;5.73,4.8,;6.21,6.26,;3.75,3.01,;2.24,2.7,;1.42,3.61,;1.76,1.24,;2.66,.02,;1.76,-1.24,;2.24,-2.7,;3.75,-3.01,;4.24,-4.47,;5.75,-4.78,;6.77,-3.63,;6.28,-2.16,;4.77,-1.86,;8.28,-3.93,;8.9,-5.33,;10.43,-5.16,;10.73,-3.65,;9.39,-2.89,;.3,-.77,;-1.03,-1.55,;-2.38,-.77,;-2.38,.77,;-1.03,1.55,;.3,.77,)| Show InChI InChI=1S/C25H27N5O2/c31-17-19-4-8-20(9-5-19)28-25(32)22-16-29(23-3-1-12-26-24(22)23)15-18-6-10-21(11-7-18)30-14-2-13-27-30/h1-3,6-7,10-14,16,19-20,31H,4-5,8-9,15,17H2,(H,28,32)/t19-,20-	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	248	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human M1 receptor expressed in CHO cells assessed as acetylcholine-induced calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 26: 650-5 (2016) Article DOI: 10.1016/j.bmcl.2015.11.053 BindingDB Entry DOI: 10.7270/Q29C708F
					More data for this Ligand-Target Pair