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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M1' and Ligand = 'BDBM50135209'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50135209
PNG
(CHEMBL3746322)
Show SMILES O[C@H]1CCCC[C@@H]1NC(=O)c1nn(Cc2ccc(cc2)-n2cccn2)c2ccccc12 |r|
Show InChI InChI=1S/C24H25N5O2/c30-22-9-4-2-7-20(22)26-24(31)23-19-6-1-3-8-21(19)29(27-23)16-17-10-12-18(13-11-17)28-15-5-14-25-28/h1,3,5-6,8,10-15,20,22,30H,2,4,7,9,16H2,(H,26,31)/t20-,22-/m0/s1
UniProtKB/SwissProt

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PC sid
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Similars
Article
PubMed
n/an/an/an/a 4.50E+3n/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human M1 receptor expressed in CHO cells assessed as acetylcholine-induced calcium mobilization by FLIPR assay

Bioorg Med Chem Lett 26: 650-5 (2016)


Article DOI: 10.1016/j.bmcl.2015.11.053
BindingDB Entry DOI: 10.7270/Q29C708F
More data for this
Ligand-Target Pair