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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M1' and Ligand = 'BDBM50240708'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50240708
PNG
(CHEMBL4096607)
Show SMILES Cc1cn(cn1)-c1ccc(Cc2cc3C(=O)N(Cc3cc2C)[C@H]2CCOC[C@@H]2O)cc1 |r|
Show InChI InChI=1S/C25H27N3O3/c1-16-9-20-13-28(23-7-8-31-14-24(23)29)25(30)22(20)11-19(16)10-18-3-5-21(6-4-18)27-12-17(2)26-15-27/h3-6,9,11-12,15,23-24,29H,7-8,10,13-14H2,1-2H3/t23-,24-/m0/s1
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PC sid
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Similars
Article
PubMed
n/an/an/an/a 45n/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human muscarinic acetylcholine receptor M1 expressed in CHO cells assessed as increase in acetylcholine-induced cal...

J Med Chem 60: 6649-6663 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00597
BindingDB Entry DOI: 10.7270/Q2ZK5JS0
More data for this
Ligand-Target Pair