Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M1' and Ligand = 'BDBM50280535'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50280535 ((2'R)-2'-methylspiro[4-azabicyclo[2.2.2]octane-2,5...) Show SMILES C[C@@H]1OC2(CS1)CN1CCC2CC1 |wU:1.0,TLB:4:3:11.12:9.8,THB:2:3:11.12:9.8,(.21,-.57,;1.01,-1.91,;.38,-3.34,;1.55,-4.38,;2.87,-3.58,;2.54,-2.07,;.71,-5.22,;.71,-6.59,;2.3,-7.55,;3.1,-6.4,;1.55,-5.48,;-.16,-6.25,;-.96,-7.48,)| Show InChI InChI=1S/C10H17NOS/c1-8-12-10(7-13-8)6-11-4-2-9(10)3-5-11/h8-9H,2-7H2,1H3/t8-,10?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article	515	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro 100 nM cortex affinity to displace [3H]- -CD providing a measure of muscarinic m1 receptor agonist affinity				Bioorg Med Chem Lett 2: 815-820 (1992) Article DOI: 10.1016/S0960-894X(00)80537-5 BindingDB Entry DOI: 10.7270/Q23X8734
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50280535 ((2'R)-2'-methylspiro[4-azabicyclo[2.2.2]octane-2,5...) Show SMILES C[C@@H]1OC2(CS1)CN1CCC2CC1 |wU:1.0,TLB:4:3:11.12:9.8,THB:2:3:11.12:9.8,(.21,-.57,;1.01,-1.91,;.38,-3.34,;1.55,-4.38,;2.87,-3.58,;2.54,-2.07,;.71,-5.22,;.71,-6.59,;2.3,-7.55,;3.1,-6.4,;1.55,-5.48,;-.16,-6.25,;-.96,-7.48,)| Show InChI InChI=1S/C10H17NOS/c1-8-12-10(7-13-8)6-11-4-2-9(10)3-5-11/h8-9H,2-7H2,1H3/t8-,10?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article	1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro 100 nM cortex affinity to displace [3H]- -pirenzepine providing a measure of muscarinic m1 receptor antagonist affinity				Bioorg Med Chem Lett 2: 815-820 (1992) Article DOI: 10.1016/S0960-894X(00)80537-5 BindingDB Entry DOI: 10.7270/Q23X8734
					More data for this Ligand-Target Pair