Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M1' and Ligand = 'BDBM50280546'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50280546 (8-Methyl-2-phenyl-1,3-dioxa-8-aza-spiro[4.5]decane...) Show SMILES CN1CCC2(COC(O2)c2ccccc2)CC1 Show InChI InChI=1S/C14H19NO2/c1-15-9-7-14(8-10-15)11-16-13(17-14)12-5-3-2-4-6-12/h2-6,13H,7-11H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	620	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro 100 nM cortex affinity to displace [3H]- -pirenzepine providing a measure of muscarinic m1 receptor antagonist affinity				Bioorg Med Chem Lett 2: 815-820 (1992) Article DOI: 10.1016/S0960-894X(00)80537-5 BindingDB Entry DOI: 10.7270/Q23X8734
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50280546 (8-Methyl-2-phenyl-1,3-dioxa-8-aza-spiro[4.5]decane...) Show SMILES CN1CCC2(COC(O2)c2ccccc2)CC1 Show InChI InChI=1S/C14H19NO2/c1-15-9-7-14(8-10-15)11-16-13(17-14)12-5-3-2-4-6-12/h2-6,13H,7-11H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro 100 nM cortex affinity to displace [3H]- -CD providing a measure of muscarinic m1 receptor agonist affinity				Bioorg Med Chem Lett 2: 815-820 (1992) Article DOI: 10.1016/S0960-894X(00)80537-5 BindingDB Entry DOI: 10.7270/Q23X8734
					More data for this Ligand-Target Pair