Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M1' and Ligand = 'BDBM50280553'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50280553 (8-Methyl-2,2-diphenyl-1,3-dioxa-8-aza-spiro[4.5]de...) Show SMILES CN1CCC2(COC(O2)(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C20H23NO2/c1-21-14-12-19(13-15-21)16-22-20(23-19,17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-11H,12-16H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro 100 nM cortex affinity to displace [3H]- -CD providing a measure of muscarinic m1 receptor agonist affinity				Bioorg Med Chem Lett 2: 815-820 (1992) Article DOI: 10.1016/S0960-894X(00)80537-5 BindingDB Entry DOI: 10.7270/Q23X8734
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50280553 (8-Methyl-2,2-diphenyl-1,3-dioxa-8-aza-spiro[4.5]de...) Show SMILES CN1CCC2(COC(O2)(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C20H23NO2/c1-21-14-12-19(13-15-21)16-22-20(23-19,17-8-4-2-5-9-17)18-10-6-3-7-11-18/h2-11H,12-16H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	8.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro 100 nM cortex affinity to displace [3H]- -CD providing a measure of muscarinic m1 receptor agonist affinity				Bioorg Med Chem Lett 2: 815-820 (1992) Article DOI: 10.1016/S0960-894X(00)80537-5 BindingDB Entry DOI: 10.7270/Q23X8734
					More data for this Ligand-Target Pair