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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M1' and Ligand = 'BDBM50326227'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50326227
PNG
(CHEMBL1243386 | N-{1-[3-(8-Fluoro-2-oxo-3,4-dihydr...)
Show SMILES CCC(=O)NC1CCN(CCCN2C(=O)CCc3cccc(F)c23)CC1
Show InChI InChI=1S/C20H28FN3O2/c1-2-18(25)22-16-9-13-23(14-10-16)11-4-12-24-19(26)8-7-15-5-3-6-17(21)20(15)24/h3,5-6,16H,2,4,7-14H2,1H3,(H,22,25)
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Similars
Article
PubMed
n/an/an/an/a 310n/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assay

J Med Chem 53: 6386-97 (2010)


Article DOI: 10.1021/jm100697g
BindingDB Entry DOI: 10.7270/Q2765G9K
More data for this
Ligand-Target Pair