Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M3' and Ligand = 'BDBM325608'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM325608 (US9636336, Example 78c) Show SMILES COc1ccc(cc1OC)[C@H](Cc1c(Cl)c[n+]([O-])cc1Cl)OC(=O)c1ccc(CNC(C(=O)O[C@H]2CCN(C)C2)c2ccccc2)s1 |r| Show InChI InChI=1S/C34H35Cl2N3O7S/c1-38-14-13-23(18-38)45-34(41)32(21-7-5-4-6-8-21)37-17-24-10-12-31(47-24)33(40)46-29(16-25-26(35)19-39(42)20-27(25)36)22-9-11-28(43-2)30(15-22)44-3/h4-12,15,19-20,23,29,32,37H,13-14,16-18H2,1-3H3/t23-,29-,32?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CHIESI FARMACEUTICI S.p.A. US Patent					Assay Description Human M3 receptor membranes (15 μg/well) from Perkin Elmer are incubated with 0.52 nM Scopolamine Methyl Chloride, [N-methyl-3H] with or without...				US Patent US9636336 (2017) BindingDB Entry DOI: 10.7270/Q2JS9SH5
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM325608 (US9636336, Example 78c) Show SMILES COc1ccc(cc1OC)[C@H](Cc1c(Cl)c[n+]([O-])cc1Cl)OC(=O)c1ccc(CNC(C(=O)O[C@H]2CCN(C)C2)c2ccccc2)s1 |r| Show InChI InChI=1S/C34H35Cl2N3O7S/c1-38-14-13-23(18-38)45-34(41)32(21-7-5-4-6-8-21)37-17-24-10-12-31(47-24)33(40)46-29(16-25-26(35)19-39(42)20-27(25)36)22-9-11-28(43-2)30(15-22)44-3/h4-12,15,19-20,23,29,32,37H,13-14,16-18H2,1-3H3/t23-,29-,32?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.08	n/a	n/a	n/a	n/a	n/a	n/a
CHIESI FARMACEUTICI S.p.A. US Patent					Assay Description Human M3 receptor membranes (15 μg/well) from Perkin Elmer are incubated with 0.52 nM Scopolamine Methyl Chloride, [N-methyl-3H] with or without...				US Patent US9636336 (2017) BindingDB Entry DOI: 10.7270/Q2JS9SH5
					More data for this Ligand-Target Pair