Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M3' and Ligand = 'BDBM354663'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM354663 (US9809582, Example 5) Show SMILES COc1ccc(cc1OC)[C@H](Cc1c(Cl)c[n+]([O-])cc1Cl)OC(=O)c1ccc(CNCC(C(=O)OC2CCN(C)CC2)c2ccccc2)s1 |r| Show InChI InChI=1S/C36H39Cl2N3O7S/c1-40-15-13-25(14-16-40)47-35(42)28(23-7-5-4-6-8-23)20-39-19-26-10-12-34(49-26)36(43)48-32(18-27-29(37)21-41(44)22-30(27)38)24-9-11-31(45-2)33(17-24)46-3/h4-12,17,21-22,25,28,32,39H,13-16,18-20H2,1-3H3/t28?,32-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
CHIESI FARMACEUTICI S.p.A. US Patent					Assay Description Human M3 receptor membranes (15 μg/well) from Perkin Elmer are incubated with 0.52 nM Scopolamine Methyl Chloride, [N-methyl-3H] with or without...				US Patent US9809582 (2017) BindingDB Entry DOI: 10.7270/Q2H1345N
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