Found 65 hits Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M3' and Ligand = 'BDBM50004656' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
Reactome pathway KEGG
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| Article PubMed
| 700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description Displacement of [3H]NMS from rat M3'(3C)-Xa receptor F92C/F550C mutant expressed in african green monkey COS7 cells |
J Biol Chem 282: 26284-93 (2007)
Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
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| Article PubMed
| 990 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description Displacement of [3H]NMS from rat M3'(3C)-Xa receptor F92C/R551C mutant expressed in african green monkey COS7 cells |
J Biol Chem 282: 26284-93 (2007)
Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
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| 1.04E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description Displacement of [3H]NMS from rat M3'(3C)-Xa receptor F92C/T549C mutant expressed in african green monkey COS7 cells |
J Biol Chem 282: 26284-93 (2007)
Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
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| 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description Displacement of [3H]NMS from rat M3'(3C)-Xa receptor F92C/K548C mutant expressed in african green monkey COS7 cells |
J Biol Chem 282: 26284-93 (2007)
Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
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| Article PubMed
| 3.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description Displacement of [3H]NMS from rat M3'(3C)-Xa receptor K93C/F550C mutant expressed in african green monkey COS7 cells |
J Biol Chem 282: 26284-93 (2007)
Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
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| Article PubMed
| 3.41E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description Displacement of [3H]NMS from rat M3'(3C)-Xa receptor N95C/R551C mutant expressed in african green monkey COS7 cells |
J Biol Chem 282: 26284-93 (2007)
Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
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| Article PubMed
| 3.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description Displacement of [3H]NMS from rat M3'(3C)-Xa receptor N95C/F550C mutant expressed in african green monkey COS7 cells |
J Biol Chem 282: 26284-93 (2007)
Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
Reactome pathway KEGG
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| Article PubMed
| 4.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description Displacement of [3H]NMS from rat M3'(3C)-Xa receptor A91C/F550C mutant expressed in african green monkey COS7 cells |
J Biol Chem 282: 26284-93 (2007)
Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
Reactome pathway KEGG
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| Article PubMed
| 4.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description Displacement of [3H]NMS from rat M3'(3C)-Xa receptor N95C/T549C mutant expressed in african green monkey COS7 cells |
J Biol Chem 282: 26284-93 (2007)
Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
Reactome pathway KEGG
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| Article PubMed
| 4.68E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description Displacement of [3H]NMS from rat M3'(3C)-Xa receptor V94C/R551C mutant expressed in african green monkey COS7 cells |
J Biol Chem 282: 26284-93 (2007)
Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
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| Article PubMed
| 4.95E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description Displacement of [3H]NMS from rat M3'(3C)-Xa receptor A91C/K548C mutant expressed in african green monkey COS7 cells |
J Biol Chem 282: 26284-93 (2007)
Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
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| Article PubMed
| 5.41E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description Displacement of [3H]NMS from rat M3'(3C)-Xa receptor K93C/T549C mutant expressed in african green monkey COS7 cells |
J Biol Chem 282: 26284-93 (2007)
Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
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| Article PubMed
| 5.52E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description Displacement of [3H]NMS from rat M3'(3C)-Xa receptor N95C/K548C mutant expressed in african green monkey COS7 cells |
J Biol Chem 282: 26284-93 (2007)
Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
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| 5.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description Displacement of [3H]NMS from rat M3'(3C)-Xa receptor A91C/T549C mutant expressed in african green monkey COS7 cells |
J Biol Chem 282: 26284-93 (2007)
Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
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| Article PubMed
| 6.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description Displacement of [3H]NMS from rat M3'(3C)-Xa receptor K93C/R551C mutant expressed in african green monkey COS7 cells |
J Biol Chem 282: 26284-93 (2007)
Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
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| Article PubMed
| 6.57E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description Displacement of [3H]NMS from rat M3'(3C)-Xa receptor A91C/R551C mutant expressed in african green monkey COS7 cells |
J Biol Chem 282: 26284-93 (2007)
Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
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| Article PubMed
| 6.82E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description Displacement of [3H]NMS from rat M3'(3C)-Xa receptor V94C/F550C mutant expressed in african green monkey COS7 cells |
J Biol Chem 282: 26284-93 (2007)
Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
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| Article PubMed
| 7.69E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description Displacement of [3H]NMS from rat M3'(3C)-Xa receptor V94C/T549C mutant expressed in african green monkey COS7 cells |
J Biol Chem 282: 26284-93 (2007)
Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
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| 9.14E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description Displacement of [3H]NMS from rat M3'(3C)-Xa receptor K93C/K548C mutant expressed in african green monkey COS7 cells |
J Biol Chem 282: 26284-93 (2007)
Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(Homo sapiens (Human)) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
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| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arkansas
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 303: 29-35 (2002)
Article DOI: 10.1124/jpet.102.036376 BindingDB Entry DOI: 10.7270/Q20R9N0G |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
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| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arkansas
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 303: 29-35 (2002)
Article DOI: 10.1124/jpet.102.036376 BindingDB Entry DOI: 10.7270/Q20R9N0G |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
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| 1.38E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description Displacement of [3H]NMS from rat M3'(3C)-Xa receptor V94C/K548C mutant expressed in african green monkey COS7 cells |
J Biol Chem 282: 26284-93 (2007)
Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(Homo sapiens (Human)) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
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| Article PubMed
| 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Chapel Hill
Curated by ChEMBL
| Assay Description Binding affinity of compound was determined towards human Muscarinic acetylcholine receptor M3 using [3H]-QNB radioligand |
J Med Chem 46: 2216-26 (2003)
Article DOI: 10.1021/jm020572p BindingDB Entry DOI: 10.7270/Q2GB23DS |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(Homo sapiens (Human)) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
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| Article PubMed
| 4.37E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Camerino
Curated by ChEMBL
| Assay Description Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO cells by microplate scintillation counting |
Bioorg Med Chem 17: 8174-85 (2009)
Article DOI: 10.1016/j.bmc.2009.10.027 BindingDB Entry DOI: 10.7270/Q2125TW3 |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(Homo sapiens (Human)) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| 4.37E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Firenze
Curated by ChEMBL
| Assay Description Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO cells by liquid scintillation counter |
J Med Chem 51: 3905-12 (2008)
Article DOI: 10.1021/jm800145d BindingDB Entry DOI: 10.7270/Q2TX3GMC |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(Homo sapiens (Human)) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| 4.37E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Camerino
Curated by ChEMBL
| Assay Description Displacement of [3H]NMS from human cloned muscarinic M3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 18: 614-8 (2008)
Checked by Author Article DOI: 10.1016/j.bmcl.2007.11.073 BindingDB Entry DOI: 10.7270/Q2XP76FV |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(Homo sapiens (Human)) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| 4.37E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Camerino
Curated by ChEMBL
| Assay Description Displacement of [3H]NMS from human muscarinic M3 receptor transfected in CHO cells after 120 mins by scintillation counting analysis |
Bioorg Med Chem Lett 24: 3255-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.020 BindingDB Entry DOI: 10.7270/Q2WW7KBT |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(Homo sapiens (Human)) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| 4.37E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Firenze
Curated by ChEMBL
| Assay Description Binding affinity to cloned human muscarinic M3 receptor expressed in CHO cells |
J Med Chem 49: 1925-31 (2006)
Article DOI: 10.1021/jm0510878 BindingDB Entry DOI: 10.7270/Q2HX1GFK |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(Homo sapiens (Human)) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| 5.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Displacement of [3H]N-methyl-scopolamine bromide from human recombinant muscarinic M3 receptor expressed in HEK293T cell membranes after 1 hr by liqu... |
J Med Chem 60: 9239-9250 (2017)
Article DOI: 10.1021/acs.jmedchem.7b01113 BindingDB Entry DOI: 10.7270/Q2445PW2 |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(Homo sapiens (Human)) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| PubMed
| n/a | n/a | 880 | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Pharmaceutical Research
Curated by ChEMBL
| Assay Description Compound was evaluated for its binding affinity at human muscarinic receptor m3 by the displacement of [3H]NMS radioligand using membranes from trans... |
Bioorg Med Chem Lett 8: 1991-6 (1999)
BindingDB Entry DOI: 10.7270/Q2FB53F2 |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(Homo sapiens (Human)) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 9.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description In vitro affinity of the compound is evaluated, using quinuclidynyl benzylate (QNB) as radioligand in human cloned Muscarinic acetylcholine receptor ... |
J Med Chem 40: 4265-80 (1998)
Article DOI: 10.1021/jm9702903 BindingDB Entry DOI: 10.7270/Q2S46R2D |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
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CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 5.62E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description Inhibition of disulfide bond cross-linking formation in rat M3'(3C)-Xa receptor F92C/F550C mutant expressed in african green monkey COS7 cells by sca... |
J Biol Chem 282: 26284-93 (2007)
Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 8.18E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description Inhibition of disulfide bond cross-linking formation in rat M3'(3C)-Xa receptor A91C/T549C mutant expressed in african green monkey COS7 cells by sca... |
J Biol Chem 282: 26284-93 (2007)
Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 197 | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description Agonist activity at rat M3'(3C)-Xa receptor K93C/T549C mutant expressed in african green monkey COS7 cells assessed as increase in myo-[3H]inositol h... |
J Biol Chem 282: 26284-93 (2007)
Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 66 | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description Agonist activity at rat M3'(3C)-Xa receptor K93C/F550C mutant expressed in african green monkey COS7 cells assessed as increase in myo-[3H]inositol h... |
J Biol Chem 282: 26284-93 (2007)
Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 134 | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description Agonist activity at rat M3'(3C)-Xa receptor K93C/R551C mutant expressed in african green monkey COS7 cells assessed as increase in myo-[3H]inositol h... |
J Biol Chem 282: 26284-93 (2007)
Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 40 | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description Agonist activity at rat M3'(3C)-Xa receptor V94C/T549C mutant expressed in african green monkey COS7 cells assessed as increase in myo-[3H]inositol h... |
J Biol Chem 282: 26284-93 (2007)
Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 300 | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description Agonist activity at rat M3'(3C)-Xa receptor V94C/F550C mutant expressed in african green monkey COS7 cells assessed as increase in myo-[3H]inositol h... |
J Biol Chem 282: 26284-93 (2007)
Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 423 | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description Agonist activity at rat M3'(3C)-Xa receptor N95C/T549C mutant expressed in african green monkey COS7 cells assessed as increase in myo-[3H]inositol h... |
J Biol Chem 282: 26284-93 (2007)
Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 120 | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description Agonist activity at rat M3'(3C)-Xa receptor N95C/F550C mutant expressed in african green monkey COS7 cells assessed as increase in myo-[3H]inositol h... |
J Biol Chem 282: 26284-93 (2007)
Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.21E+4 | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description Agonist activity at rat M3'(3C)-Xa receptor N95C/R551C mutant expressed in african green monkey COS7 cells assessed as increase in myo-[3H]inositol h... |
J Biol Chem 282: 26284-93 (2007)
Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 90 | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description Agonist activity at rat M3'(3C)-Xa receptor F92C/R551C mutant expressed in african green monkey COS7 cells assessed as increase in myo-[3H]inositol h... |
J Biol Chem 282: 26284-93 (2007)
Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 21 | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description Agonist activity at rat M3'(3C)-Xa receptor A91C/T549C mutant expressed in african green monkey COS7 cells assessed as increase in myo-[3H]inositol h... |
J Biol Chem 282: 26284-93 (2007)
Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description Agonist activity at rat M3'(3C)-Xa receptor F92C/F550C mutant expressed in african green monkey COS7 cells assessed as increase in myo-[3H]inositol h... |
J Biol Chem 282: 26284-93 (2007)
Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 67 | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description Agonist activity at rat M3'(3C)-Xa receptor V94C/K548C mutant expressed in african green monkey COS7 cells assessed as increase in myo-[3H]inositol h... |
J Biol Chem 282: 26284-93 (2007)
Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 35 | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description Agonist activity at rat M3'(3C)-Xa receptor F92C/T549C mutant expressed in african green monkey COS7 cells assessed as increase in myo-[3H]inositol h... |
J Biol Chem 282: 26284-93 (2007)
Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 130 | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description Agonist activity at rat M3'(3C)-Xa receptor V94C/R551C mutant expressed in african green monkey COS7 cells assessed as increase in myo-[3H]inositol h... |
J Biol Chem 282: 26284-93 (2007)
Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 148 | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description Agonist activity at rat M3'(3C)-Xa receptor N95C/K548C mutant expressed in african green monkey COS7 cells assessed as increase in myo-[3H]inositol h... |
J Biol Chem 282: 26284-93 (2007)
Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(RAT) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
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CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 38 | n/a | n/a | n/a | n/a |
NIDDK
Curated by ChEMBL
| Assay Description Agonist activity at rat M3'(3C)-Xa receptor A91C/K548C mutant expressed in african green monkey COS7 cells assessed as increase in myo-[3H]inositol h... |
J Biol Chem 282: 26284-93 (2007)
Article DOI: 10.1074/jbc.m704875200 BindingDB Entry DOI: 10.7270/Q25D8VMR |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M3
(Homo sapiens (Human)) | BDBM50004656
((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...)Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 25 | n/a | n/a | n/a | n/a |
Friedrich-Alexander-Universit£t Erlangen-N£rnberg
Curated by ChEMBL
| Assay Description Agonist activity at human muscarinic M3 receptor expressed in HEK293 cells assessed as increase in IP1 accumulation incubated for 90 min by TR-HTRF a... |
J Med Chem 63: 4349-4369 (2020)
Article DOI: 10.1021/acs.jmedchem.0c00297 BindingDB Entry DOI: 10.7270/Q2CR5XWB |
More data for this Ligand-Target Pair | |