BindingDB PrimarySearch

Found 13 hits Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M3' and Ligand = 'BDBM50064176'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50064176 (CHEMBL27673 \| CHEMBL500996 \| METHOCTRAMINE \| N,N''...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	118	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by PDSP K_i Database									Mol Pharmacol 35: 469-76 (1989) BindingDB Entry DOI: 10.7270/Q2V69H2Z
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (RAT)	BDBM50064176 (CHEMBL27673 \| CHEMBL500996 \| METHOCTRAMINE \| N,N''...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	132	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Group Research Ltd. Curated by PDSP K_i Database									Mol Pharmacol 38: 805-15 (1990) BindingDB Entry DOI: 10.7270/Q2H993P0
Glaxo Group Research Ltd. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50064176 (CHEMBL27673 \| CHEMBL500996 \| METHOCTRAMINE \| N,N''...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	214	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Neurological Disorders and Stroke Curated by PDSP K_i Database									J Pharmacol Exp Ther 256: 727-33 (1991) BindingDB Entry DOI: 10.7270/Q2VD6WZ3
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50064176 (CHEMBL27673 \| CHEMBL500996 \| METHOCTRAMINE \| N,N''...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	277	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Affinity for human M3 cloned muscarinic receptor subtype expressed in CHO-K1 cells				J Med Chem 44: 4035-8 (2001) BindingDB Entry DOI: 10.7270/Q21R6PTT
University of Bologna Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50064176 (CHEMBL27673 \| CHEMBL500996 \| METHOCTRAMINE \| N,N''...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	277	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pisa Curated by PDSP K_i Database									Eur J Pharmacol 268: 459-62 (1994) Article DOI: 10.1016/0922-4106(94)90075-2 BindingDB Entry DOI: 10.7270/Q2348HWT
University of Pisa Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (RAT)	BDBM50064176 (CHEMBL27673 \| CHEMBL500996 \| METHOCTRAMINE \| N,N''...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	316	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute for Medical Research Curated by PDSP K_i Database									Annu Rev Pharmacol Toxicol 30: 633-73 (1990) Article DOI: 10.1146/annurev.pa.30.040190.003221 BindingDB Entry DOI: 10.7270/Q21Z42WK
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (RAT)	BDBM50064176 (CHEMBL27673 \| CHEMBL500996 \| METHOCTRAMINE \| N,N''...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	955	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Inhibition of [3H]NMS binding to rat submaxillary gland Muscarinic acetylcholine receptor M3				J Med Chem 41: 4150-60 (1998) Checked by Author Article DOI: 10.1021/jm981038d BindingDB Entry DOI: 10.7270/Q2KH0PJH
University of Bologna Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (RAT)	BDBM50064176 (CHEMBL27673 \| CHEMBL500996 \| METHOCTRAMINE \| N,N''...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	998	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Compound was tested for its binding affinity towards Muscarinic acetylcholine receptor M3 using [3H]-NMS from rat submaxillary gland				J Med Chem 41: 1557-60 (1998) Article DOI: 10.1021/jm970740r BindingDB Entry DOI: 10.7270/Q2N29W3Q
University of Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (RAT)	BDBM50064176 (CHEMBL27673 \| CHEMBL500996 \| METHOCTRAMINE \| N,N''...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars		1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of binding of [3H]N-methylscopolamine to muscarinic receptor (M3) in rat submaxillary gland homogenates				Citation and Details BindingDB Entry DOI: 10.7270/Q2ZK5JTF
TBA					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (RAT)	BDBM50064176 (CHEMBL27673 \| CHEMBL500996 \| METHOCTRAMINE \| N,N''...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by PDSP K_i Database									J Med Chem 36: 3734-7 (1993) Article DOI: 10.1021/jm00075a032 BindingDB Entry DOI: 10.7270/Q2W957Q0
University of Bologna Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (RAT)	BDBM50064176 (CHEMBL27673 \| CHEMBL500996 \| METHOCTRAMINE \| N,N''...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Creighton University Curated by PDSP K_i Database									J Pharmacol Exp Ther 297: 718-26 (2001) BindingDB Entry DOI: 10.7270/Q28G8J85
Creighton University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (RAT)	BDBM50064176 (CHEMBL27673 \| CHEMBL500996 \| METHOCTRAMINE \| N,N''...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Creighton University Curated by PDSP K_i Database									J Pharmacol Exp Ther 297: 718-26 (2001) BindingDB Entry DOI: 10.7270/Q28G8J85
Creighton University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (RAT)	BDBM50064176 (CHEMBL27673 \| CHEMBL500996 \| METHOCTRAMINE \| N,N''...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université Libre de Bruxelles Curated by PDSP K_i Database									Mol Pharmacol 38: 267-73 (1990) BindingDB Entry DOI: 10.7270/Q2NP22X3
Université Libre de Bruxelles Curated by PDSP K_i Database					More data for this Ligand-Target Pair