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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M3' and Ligand = 'BDBM50208025'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50208025
PNG
(3-(1-(4-methoxybenzyl)-piperidin-4-yl)-5,5-dipheny...)
Show SMILES COc1ccc(CN2CCC(CC2)N2CC(NC2=O)(c2ccccc2)c2ccccc2)cc1
Show InChI InChI=1S/C28H31N3O2/c1-33-26-14-12-22(13-15-26)20-30-18-16-25(17-19-30)31-21-28(29-27(31)32,23-8-4-2-5-9-23)24-10-6-3-7-11-24/h2-15,25H,16-21H2,1H3,(H,29,32)
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PC cid
PC sid
UniChem
Article
PubMed
25.8n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M3 receptor expressed in CHO K1 cells


J Med Chem 50: 1571-83 (2007)


Article DOI: 10.1021/jm061159a
BindingDB Entry DOI: 10.7270/Q2QV3M61
More data for this
Ligand-Target Pair