Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M3' and Ligand = 'BDBM50355625'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50355625 (CHEMBL1910859) Show SMILES CC(C)(CCC(C(N)=O)(c1ccccc1)c1ccccc1)N1CC[C@@H](C1)Oc1ccc(Cl)c(O)c1 |r| Show InChI InChI=1S/C29H33ClN2O3/c1-28(2,32-18-15-24(20-32)35-23-13-14-25(30)26(33)19-23)16-17-29(27(31)34,21-9-5-3-6-10-21)22-11-7-4-8-12-22/h3-14,19,24,33H,15-18,20H2,1-2H3,(H2,31,34)/t24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant M3 receptor expressed in CHO-K1 cells assessed as inhibition of carbamoyl choline-induced calcium currents a...				J Med Chem 54: 6888-904 (2011) Article DOI: 10.1021/jm200884j BindingDB Entry DOI: 10.7270/Q2CZ37JW
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