Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M4' and Ligand = 'BDBM50174726'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174726 (CHEMBL3808696) Show SMILES Cc1sc2ncnc(N3CCC(CC3)C(=O)N3CCCC(F)(F)C3)c2c1C Show InChI InChI=1S/C19H24F2N4OS/c1-12-13(2)27-17-15(12)16(22-11-23-17)24-8-4-14(5-9-24)18(26)25-7-3-6-19(20,21)10-25/h11,14H,3-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.86E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50174726 (CHEMBL3808696) Show SMILES Cc1sc2ncnc(N3CCC(CC3)C(=O)N3CCCC(F)(F)C3)c2c1C Show InChI InChI=1S/C19H24F2N4OS/c1-12-13(2)27-17-15(12)16(22-11-23-17)24-8-4-14(5-9-24)18(26)25-7-3-6-19(20,21)10-25/h11,14H,3-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 26: 3029-33 (2016) Article DOI: 10.1016/j.bmcl.2016.05.010 BindingDB Entry DOI: 10.7270/Q2DV1MTJ
					More data for this Ligand-Target Pair