Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M5' and Ligand = 'BDBM50314599'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50314599 (CHEMBL1093933 | N-(3-chloro-4-(4-ethylpiperazin-1-...) Show SMILES CCN1CCN(CC1)c1ccc(NC(=O)c2ccc(F)c(F)c2)cc1Cl Show InChI InChI=1S/C19H20ClF2N3O/c1-2-24-7-9-25(10-8-24)18-6-4-14(12-15(18)20)23-19(26)13-3-5-16(21)17(22)11-13/h3-6,11-12H,2,7-10H2,1H3,(H,23,26)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Antagonist activity at human muscarinic M5 receptor expressed in CHO-K1 cells assessed as inhibition of acetylcholine-induced calcium mobilization				Bioorg Med Chem Lett 20: 2174-7 (2010) Article DOI: 10.1016/j.bmcl.2010.02.041 BindingDB Entry DOI: 10.7270/Q2D50N38
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