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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Myeloblastin' and Ligand = 'BDBM50263166'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Myeloblastin


(Homo sapiens (Human))		BDBM50263166
PNG
(CHEMBL4071346)
Show SMILES [H][C@]12CS[C@@H](CCCCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)N[C@@H](CC(O)=O)C(=O)NC(CCC)P(=O)(Oc3ccc(Cl)cc3)Oc3ccc(Cl)cc3)[C@@]1([H])NC(=O)N2 |r|
Show InChI InChI=1S/C44H55Cl2N6O11PS/c1-4-7-37(64(61,62-30-18-12-27(45)13-19-30)63-31-20-14-28(46)15-21-31)51-42(58)33(23-38(55)56)47-41(57)32(22-26-10-16-29(53)17-11-26)48-43(59)39(25(2)3)50-36(54)9-6-5-8-35-40-34(24-65-35)49-44(60)52-40/h10-21,25,32-35,37,39-40,53H,4-9,22-24H2,1-3H3,(H,47,57)(H,48,59)(H,50,54)(H,51,58)(H,55,56)(H2,49,52,60)/t32-,33-,34-,35-,37?,39-,40-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
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PC cid
PC sid
UniChem

Similars
Article
PubMed
 5.40n/an/an/an/an/an/an/an/a



INSERM UMR1100,"Centre d'Etude des Pathologies Respiratoires" , Université de Tours , 37032 Tours , France.

Curated by ChEMBL


Assay Description
Inhibition of human PR3 using ABZ-VADnVADYQ-EDDnp as substrate by FRET assay

J Med Chem 61: 1858-1870 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01416
BindingDB Entry DOI: 10.7270/Q25B04ZT
More data for this
Ligand-Target Pair