Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'N-acylethanolamine-hydrolyzing acid amidase' and Ligand = 'BDBM50416510'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N-acylethanolamine-hydrolyzing acid amidase (Rattus norvegicus (Rat))	BDBM50416510 (CHEMBL1214257 | US9321743, URB818) Show SMILES O=C(CCc1ccccc1)N[C@@H]1COC1=O |r| Show InChI InChI=1S/C12H13NO3/c14-11(13-10-8-16-12(10)15)7-6-9-4-2-1-3-5-9/h1-5,10H,6-8H2,(H,13,14)/t10-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	5.0	37
The Regents of the University of California; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo” US Patent					Assay Description Recombinant NAAA or native rat lung NAAA was incubated at 37 °C. for 30 min in 0.2 ml of sodium hydrogen phosphate buffer (50 mM, pH 5.0) contain...				US Patent US9321743 (2016) BindingDB Entry DOI: 10.7270/Q26D5RVT
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Rattus norvegicus (Rat))	BDBM50416510 (CHEMBL1214257 | US9321743, URB818) Show SMILES O=C(CCc1ccccc1)N[C@@H]1COC1=O |r| Show InChI InChI=1S/C12H13NO3/c14-11(13-10-8-16-12(10)15)7-6-9-4-2-1-3-5-9/h1-5,10H,6-8H2,(H,13,14)/t10-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of rat NAAA				J Med Chem 63: 7475-7490 (2020) Article DOI: 10.1021/acs.jmedchem.0c00191 BindingDB Entry DOI: 10.7270/Q2V98CM4
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Rattus norvegicus (Rat))	BDBM50416510 (CHEMBL1214257 | US9321743, URB818) Show SMILES O=C(CCc1ccccc1)N[C@@H]1COC1=O |r| Show InChI InChI=1S/C12H13NO3/c14-11(13-10-8-16-12(10)15)7-6-9-4-2-1-3-5-9/h1-5,10H,6-8H2,(H,13,14)/t10-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of rat recombinant NAAA expressed in HEK293 cells after 30 mins				J Med Chem 53: 5770-81 (2010) Article DOI: 10.1021/jm100582w BindingDB Entry DOI: 10.7270/Q2X0689M
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Rattus norvegicus (Rat))	BDBM50416510 (CHEMBL1214257 | US9321743, URB818) Show SMILES O=C(CCc1ccccc1)N[C@@H]1COC1=O |r| Show InChI InChI=1S/C12H13NO3/c14-11(13-10-8-16-12(10)15)7-6-9-4-2-1-3-5-9/h1-5,10H,6-8H2,(H,13,14)/t10-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of recombinant rat lung NAAA enzyme using heptadecenoylethanolamide as substrate by LC/MS analysis				J Med Chem 56: 6917-34 (2013) Article DOI: 10.1021/jm400739u BindingDB Entry DOI: 10.7270/Q2F47QK0
					More data for this Ligand-Target Pair