Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'NAD-dependent protein deacetylase sirtuin-1' and Ligand = 'BDBM50397041'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-dependent protein deacetylase sirtuin-1 (Homo sapiens (Human))	BDBM50397041 (CHEMBL2171199) Show SMILES CCn1c(=O)nc2oc3ccccc3cc2c1=O Show InChI InChI=1S/C13H10N2O3/c1-2-15-12(16)9-7-8-5-3-4-6-10(8)18-11(9)14-13(15)17/h3-7H,2H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.18E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of human recombinant SIRT1 expressed in Escherichia coli cells using acetylated Lys side chain amino acids 379-382 (Arg-His-Lys-Lys(Ac)) p...				J Med Chem 55: 8193-7 (2012) Article DOI: 10.1021/jm301115r BindingDB Entry DOI: 10.7270/Q2JW8G0C
					More data for this Ligand-Target Pair