Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'NAD-dependent protein deacetylase sirtuin-1' and Ligand = 'BDBM50400328'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-dependent protein deacetylase sirtuin-1 (Homo sapiens (Human))	BDBM50400328 (CHEMBL2181510) Show SMILES CC(CS(=O)(=O)c1cccc(c1)\N=C\c1c(O)ccc2ccccc12)c1ccccc1 Show InChI InChI=1S/C26H23NO3S/c1-19(20-8-3-2-4-9-20)18-31(29,30)23-12-7-11-22(16-23)27-17-25-24-13-6-5-10-21(24)14-15-26(25)28/h2-17,19,28H,18H2,1H3/b27-17+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of human N-terminal GST-tagged SIRT1 expressed in Escherichia coli using Arg-His- Lys-Lys(Ac) as substrate after 1 hr by Fluor de Lys fluo...				J Med Chem 55: 10937-47 (2012) Article DOI: 10.1021/jm3011614 BindingDB Entry DOI: 10.7270/Q28G8MVM
					More data for this Ligand-Target Pair