Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'NAD-dependent protein deacetylase sirtuin-2' and Ligand = 'BDBM50096905'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50096905 (CHEMBL3580803) Show SMILES Clc1ccc(CSc2cccc(c2)C(=O)Nc2ccc(cc2)C#N)cc1 Show InChI InChI=1S/C21H15ClN2OS/c22-18-8-4-16(5-9-18)14-26-20-3-1-2-17(12-20)21(25)24-19-10-6-15(13-23)7-11-19/h1-12H,14H2,(H,24,25)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Inhibition of SIRT2 (unknown origin) by Flour-de-Lys fluorescent biochemical assay				ACS Med Chem Lett 6: 607-11 (2015) Article DOI: 10.1021/acsmedchemlett.5b00075 BindingDB Entry DOI: 10.7270/Q2XS5X4S
					More data for this Ligand-Target Pair