Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'NAD-dependent protein deacetylase sirtuin-2' and Ligand = 'BDBM50168849'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50168849 (CHEMBL3805427) Show SMILES CC(=O)Nc1ccc(cc1)C(=O)Nc1cccc(COc2cncc(c2)C(N)=O)c1 Show InChI InChI=1S/C22H20N4O4/c1-14(27)25-18-7-5-16(6-8-18)22(29)26-19-4-2-3-15(9-19)13-30-20-10-17(21(23)28)11-24-12-20/h2-12H,13H2,1H3,(H2,23,28)(H,25,27)(H,26,29)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 residues) expressed in Escherichia coli using Ac-RHK-K(Ac)-AMC as substrate in...				J Med Chem 59: 2928-41 (2016) Article DOI: 10.1021/acs.jmedchem.5b01376 BindingDB Entry DOI: 10.7270/Q2Z89F9W
					More data for this Ligand-Target Pair