Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'NAD-dependent protein deacylase sirtuin-6' and Ligand = 'BDBM50123401'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-dependent protein deacylase sirtuin-6 (Homo sapiens (Human))	BDBM50123401 (CHEMBL3623257) Show SMILES O=C1CCc2cc(ccc2N1)S(=O)(=O)Nc1ccc(Oc2cccnc2)cc1 Show InChI InChI=1S/C20H17N3O4S/c24-20-10-3-14-12-18(8-9-19(14)22-20)28(25,26)23-15-4-6-16(7-5-15)27-17-2-1-11-21-13-17/h1-2,4-9,11-13,23H,3,10H2,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Inhibition of human SIRT6 deacetylase activity using Arg-His-Lys-Lys(AC)-AMC as a substrate by fluorescence assay				Eur J Med Chem 102: 530-9 (2015) Article DOI: 10.1016/j.ejmech.2015.08.024 BindingDB Entry DOI: 10.7270/Q2K35WGV
					More data for this Ligand-Target Pair
NAD-dependent protein deacylase sirtuin-6 (Homo sapiens (Human))	BDBM50123401 (CHEMBL3623257) Show SMILES O=C1CCc2cc(ccc2N1)S(=O)(=O)Nc1ccc(Oc2cccnc2)cc1 Show InChI InChI=1S/C20H17N3O4S/c24-20-10-3-14-12-18(8-9-19(14)22-20)28(25,26)23-15-4-6-16(7-5-15)27-17-2-1-11-21-13-17/h1-2,4-9,11-13,23H,3,10H2,(H,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.75E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Genoa Curated by ChEMBL					Assay Description Inhibition of human recombinant SIRT6 deacetylase activity using Arg-His-Lys-Lys(AC)-AMC as a substrate by luminescence assay				Eur J Med Chem 102: 530-9 (2015) Article DOI: 10.1016/j.ejmech.2015.08.024 BindingDB Entry DOI: 10.7270/Q2K35WGV
					More data for this Ligand-Target Pair