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Found 1 hit Enz. Inhib. hit(s) with Target = 'NADPH oxidase 4' and Ligand = 'BDBM50326481'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
NADPH oxidase 4


(Homo sapiens (Human))		BDBM50326481
PNG
(CHEMBL1243188 | N1-(3-aminophenyl)-N2-(4-hydroxy-3...)
Show SMILES COc1cc(CCNC(=O)C(=O)Nc2cccc(N)c2)ccc1O
Show InChI InChI=1S/C17H19N3O4/c1-24-15-9-11(5-6-14(15)21)7-8-19-16(22)17(23)20-13-4-2-3-12(18)10-13/h2-6,9-10,21H,7-8,18H2,1H3,(H,19,22)(H,20,23)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.30E+3n/an/an/an/an/an/a



Vichem Chemie Research Ltd.

Curated by ChEMBL


Assay Description
Inhibition of NOX4 expressed in HEK293 FS cells assessed as H2O2 production by H2O2/Tyr/LPO assay

J Med Chem 53: 6758-62 (2010)


Article DOI: 10.1021/jm1004368
BindingDB Entry DOI: 10.7270/Q2F18ZZ5
More data for this
Ligand-Target Pair