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Found 1 hit Enz. Inhib. hit(s) with Target = 'NADPH oxidase 4' and Ligand = 'BDBM50326488'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
NADPH oxidase 4


(Homo sapiens (Human))
BDBM50326488
PNG
(CHEMBL1243095 | N-(3-(4-hydroxy-3-methoxybenzylide...)
Show SMILES COc1cc(\C=C2/C(=O)Nc3ccc(NC(C)=O)cc23)ccc1O
Show InChI InChI=1S/C18H16N2O4/c1-10(21)19-12-4-5-15-13(9-12)14(18(23)20-15)7-11-3-6-16(22)17(8-11)24-2/h3-9,22H,1-2H3,(H,19,21)(H,20,23)/b14-7-
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.40E+3n/an/an/an/an/an/a



Vichem Chemie Research Ltd.

Curated by ChEMBL


Assay Description
Inhibition of NOX4 expressed in HEK293 FS cells assessed as H2O2 production by H2O2/Tyr/LPO assay


J Med Chem 53: 6758-62 (2010)


Article DOI: 10.1021/jm1004368
BindingDB Entry DOI: 10.7270/Q2F18ZZ5
More data for this
Ligand-Target Pair