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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'NADPH oxidase 4' and Ligand = 'BDBM50330685'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
NADPH oxidase 4


(Homo sapiens (Human))		BDBM50330685
PNG
(5-(2-(1H-indol-3-yl)ethyl)-2-(benzo[d]thiazol-2-yl...)
Show SMILES Cc1n(CCc2c[nH]c3ccccc23)c(=O)cc2[nH]n(-c3nc4ccccc4s3)c(=O)c12
Show InChI InChI=1S/C24H19N5O2S/c1-14-22-19(27-29(23(22)31)24-26-18-8-4-5-9-20(18)32-24)12-21(30)28(14)11-10-15-13-25-17-7-3-2-6-16(15)17/h2-9,12-13,25,27H,10-11H2,1H3
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Similars
Article
PubMed
 1.85E+3n/an/an/an/an/an/an/an/a



Genkyotex, S.A.

Curated by ChEMBL


Assay Description
Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPH

J Med Chem 53: 7715-30 (2010)


Article DOI: 10.1021/jm100773e
BindingDB Entry DOI: 10.7270/Q2KH0NKJ
More data for this
Ligand-Target Pair