Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'NADPH oxidase 4' and Ligand = 'BDBM50330695'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NADPH oxidase 4 (Homo sapiens (Human))	BDBM50330695 (2-(benzo[d]thiazol-2-yl)-1-benzyl-4-methyl-5-((tet...) Show SMILES Cc1n(CC2CCCO2)c(=O)cc2n(Cc3ccccc3)n(-c3nc4ccccc4s3)c(=O)c12 Show InChI InChI=1S/C26H24N4O3S/c1-17-24-21(14-23(31)28(17)16-19-10-7-13-33-19)29(15-18-8-3-2-4-9-18)30(25(24)32)26-27-20-11-5-6-12-22(20)34-26/h2-6,8-9,11-12,14,19H,7,10,13,15-16H2,1H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genkyotex, S.A. Curated by ChEMBL					Assay Description Inhibition of human NOX4 overexpressed in human PMN cell membrane assessed as ROS production by cell free assay in presence of NADPH				J Med Chem 53: 7715-30 (2010) Article DOI: 10.1021/jm100773e BindingDB Entry DOI: 10.7270/Q2KH0NKJ
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