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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neprilysin' and Ligand = 'BDBM50025918'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neprilysin


(Rattus norvegicus (Rat))		BDBM50025918
PNG
(2-(Formyl-hydroxy-amino)-N-[(3-methyl-butylcarbamo...)
Show SMILES CC(C)CCNC(=O)CNC(=O)C(Cc1ccccc1)N(O)C=O
Show InChI InChI=1S/C17H25N3O4/c1-13(2)8-9-18-16(22)11-19-17(23)15(20(24)12-21)10-14-6-4-3-5-7-14/h3-7,12-13,15,24H,8-11H2,1-2H3,(H,18,22)(H,19,23)
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n/an/a 30n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of enkephalinase purified from rat kidney.

J Med Chem 28: 1158-69 (1985)


BindingDB Entry DOI: 10.7270/Q20C4WB5
More data for this
Ligand-Target Pair