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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neprilysin' and Ligand = 'BDBM50034856'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neprilysin


(Rattus norvegicus (Rat))		BDBM50034856
PNG
((2S,4S)-5-Biphenyl-4-yl-4-(2-carboxy-ethylcarbamoy...)
Show SMILES OC(=O)CCNC(=O)[C@@H](C[C@@H](Cc1ccc(cc1)-c1nccs1)C(O)=O)Cc1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C31H30N2O5S/c34-28(35)14-15-32-29(36)26(18-21-6-10-24(11-7-21)23-4-2-1-3-5-23)20-27(31(37)38)19-22-8-12-25(13-9-22)30-33-16-17-39-30/h1-13,16-17,26-27H,14-15,18-20H2,(H,32,36)(H,34,35)(H,37,38)/t26-,27-/m1/s1
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n/an/a 19n/an/an/an/an/an/a



CIBA-GEIGY Corporation

Curated by ChEMBL


Assay Description
In vitro inhibition of rat neutral endopeptidase by using GAAP as substrate

J Med Chem 38: 1689-700 (1995)


BindingDB Entry DOI: 10.7270/Q2Z89BD0
More data for this
Ligand-Target Pair