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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neprilysin' and Ligand = 'BDBM50034867'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neprilysin


(Rattus norvegicus (Rat))		BDBM50034867
PNG
((2S,4S)-5-Biphenyl-4-yl-4-(2-carboxy-ethylcarbamoy...)
Show SMILES COCC[C@H](C[C@@H](Cc1ccc(cc1)-c1ccccc1)C(=O)NCCC(O)=O)C(O)=O
Show InChI InChI=1S/C24H29NO6/c1-31-14-12-20(24(29)30)16-21(23(28)25-13-11-22(26)27)15-17-7-9-19(10-8-17)18-5-3-2-4-6-18/h2-10,20-21H,11-16H2,1H3,(H,25,28)(H,26,27)(H,29,30)/t20-,21-/m1/s1
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n/an/a 46n/an/an/an/an/an/a



CIBA-GEIGY Corporation

Curated by ChEMBL


Assay Description
In vitro inhibition of rat neutral endopeptidase by using GAAP as substrate

J Med Chem 38: 1689-700 (1995)


BindingDB Entry DOI: 10.7270/Q2Z89BD0
More data for this
Ligand-Target Pair