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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neprilysin' and Ligand = 'BDBM50039510'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neprilysin


(Oryctolagus cuniculus (rabbit))		BDBM50039510
PNG
((S)-3-Benzylsulfanyl-2-((R)-2-mercaptomethyl-3-phe...)
Show SMILES OC(=O)[C@@H](CSCc1ccccc1)NC(=O)[C@H](CS)Cc1ccccc1
Show InChI InChI=1S/C20H23NO3S2/c22-19(17(12-25)11-15-7-3-1-4-8-15)21-18(20(23)24)14-26-13-16-9-5-2-6-10-16/h1-10,17-18,25H,11-14H2,(H,21,22)(H,23,24)/t17-,18+/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 32n/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against neutral endopeptidase (NEP)

J Med Chem 37: 2461-76 (1994)


BindingDB Entry DOI: 10.7270/Q2571B20
More data for this
Ligand-Target Pair