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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neprilysin' and Ligand = 'BDBM50190760'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neprilysin


(Homo sapiens (Human))		BDBM50190760
PNG
(2-((1-((1-benzyl-6-oxo-1,6-dihydropyridin-3-yl)car...)
Show SMILES CCCC(CC1(CCCC1)C(=O)Nc1ccc(=O)n(Cc2ccccc2)c1)C(O)=O
Show InChI InChI=1S/C24H30N2O4/c1-2-8-19(22(28)29)15-24(13-6-7-14-24)23(30)25-20-11-12-21(27)26(17-20)16-18-9-4-3-5-10-18/h3-5,9-12,17,19H,2,6-8,13-16H2,1H3,(H,25,30)(H,28,29)
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Article
PubMed
n/an/a 313n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of dog NEP

J Med Chem 49: 4409-24 (2006)


Article DOI: 10.1021/jm060133g
BindingDB Entry DOI: 10.7270/Q2930SS8
More data for this
Ligand-Target Pair