Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neprilysin' and Ligand = 'BDBM50269066'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin (Homo sapiens (Human))	BDBM50269066 (CHEMBL4088816) Show SMILES OC(=O)C(CC(=O)C1(S)CCCC1)Cc1ccc(Br)cc1 Show InChI InChI=1S/C16H19BrO3S/c17-13-5-3-11(4-6-13)9-12(15(19)20)10-14(18)16(21)7-1-2-8-16/h3-6,12,21H,1-2,7-10H2,(H,19,20)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaleads Curated by ChEMBL					Assay Description Inhibition of recombinant human neprilysin using Suc-Ala-Ala-Phe-AMC as substrate preincubated for 30 mins followed by substrate addition measured af...				Bioorg Med Chem Lett 27: 3883-3890 (2017) Article DOI: 10.1016/j.bmcl.2017.06.050 BindingDB Entry DOI: 10.7270/Q20V8G93
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