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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neprilysin' and Ligand = 'BDBM50282849'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neprilysin


(Rattus norvegicus (Rat))		BDBM50282849
PNG
(1-[2-(2-Mercaptomethyl-4-methyl-pentanoylamino)-pr...)
Show SMILES CC(C)CC(CS)C(=O)N[C@@H](C)C(=O)N1CCC[C@@H]1C(O)=O
Show InChI InChI=1S/C15H26N2O4S/c1-9(2)7-11(8-22)13(18)16-10(3)14(19)17-6-4-5-12(17)15(20)21/h9-12,22H,4-8H2,1-3H3,(H,16,18)(H,20,21)/t10-,11?,12+/m0/s1
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Similars
Article
n/an/a 10n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrate

Bioorg Med Chem Lett 4: 1783-1788 (1994)


Article DOI: 10.1016/S0960-894X(01)80371-1
BindingDB Entry DOI: 10.7270/Q2Z3204W
More data for this
Ligand-Target Pair