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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neprilysin' and Ligand = 'BDBM50282860'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neprilysin


(Rattus norvegicus (Rat))		BDBM50282860
PNG
((S)-1-[(S)-2-((2S,3R)-2-Benzyl-3-mercapto-butyryla...)
Show SMILES C[C@@H](S)[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C19H26N2O4S/c1-12(18(23)21-10-6-9-16(21)19(24)25)20-17(22)15(13(2)26)11-14-7-4-3-5-8-14/h3-5,7-8,12-13,15-16,26H,6,9-11H2,1-2H3,(H,20,22)(H,24,25)/t12-,13+,15+,16-/m0/s1
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Similars
Article
n/an/a 182n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrate

Bioorg Med Chem Lett 4: 1783-1788 (1994)


Article DOI: 10.1016/S0960-894X(01)80371-1
BindingDB Entry DOI: 10.7270/Q2Z3204W
More data for this
Ligand-Target Pair