Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neprilysin' and Ligand = 'BDBM50288074'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin (Homo sapiens (Human))	BDBM50288074 ((2-Benzyl-2-mercaptomethyl-3-phenyl-propionylamino...) Show SMILES OC(=O)CNC(=O)C(CS)(Cc1ccccc1)Cc1ccccc1 Show InChI InChI=1S/C19H21NO3S/c21-17(22)13-20-18(23)19(14-24,11-15-7-3-1-4-8-15)12-16-9-5-2-6-10-16/h1-10,24H,11-14H2,(H,20,23)(H,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	>100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of recombinant human neprilysin(NEP).				Bioorg Med Chem Lett 6: 2437-2440 (1996) Article DOI: 10.1016/0960-894X(96)00448-9 BindingDB Entry DOI: 10.7270/Q2JS9QD0
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