Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Neuromedin-B receptor' and Ligand = 'BDBM50295231'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuromedin-B receptor (Homo sapiens (Human))	BDBM50295231 ((+)-8'-methyl-11'-(2-(trifluoromethyl)phenyl)-4',5...) Show SMILES Cc1ccc2N=C3CC4(CCCC4)CC(=O)C3C(Nc2c1)c1ccccc1C(F)(F)F |t:5| Show InChI InChI=1S/C25H25F3N2O/c1-15-8-9-18-19(12-15)30-23(16-6-2-3-7-17(16)25(26,27)28)22-20(29-18)13-24(14-21(22)31)10-4-5-11-24/h2-3,6-9,12,22-23,30H,4-5,10-11,13-14H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cells				Bioorg Med Chem Lett 19: 4264-7 (2009) Article DOI: 10.1016/j.bmcl.2009.05.124 BindingDB Entry DOI: 10.7270/Q2C24WG8
					More data for this Ligand-Target Pair
Neuromedin-B receptor (Homo sapiens (Human))	BDBM50295231 ((+)-8'-methyl-11'-(2-(trifluoromethyl)phenyl)-4',5...) Show SMILES Cc1ccc2N=C3CC4(CCCC4)CC(=O)C3C(Nc2c1)c1ccccc1C(F)(F)F |t:5| Show InChI InChI=1S/C25H25F3N2O/c1-15-8-9-18-19(12-15)30-23(16-6-2-3-7-17(16)25(26,27)28)22-20(29-18)13-24(14-21(22)31)10-4-5-11-24/h2-3,6-9,12,22-23,30H,4-5,10-11,13-14H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cells				Bioorg Med Chem Lett 19: 4264-7 (2009) Article DOI: 10.1016/j.bmcl.2009.05.124 BindingDB Entry DOI: 10.7270/Q2C24WG8
					More data for this Ligand-Target Pair
Neuromedin-B receptor (Homo sapiens (Human))	BDBM50295231 ((+)-8'-methyl-11'-(2-(trifluoromethyl)phenyl)-4',5...) Show SMILES Cc1ccc2N=C3CC4(CCCC4)CC(=O)C3C(Nc2c1)c1ccccc1C(F)(F)F |t:5| Show InChI InChI=1S/C25H25F3N2O/c1-15-8-9-18-19(12-15)30-23(16-6-2-3-7-17(16)25(26,27)28)22-20(29-18)13-24(14-21(22)31)10-4-5-11-24/h2-3,6-9,12,22-23,30H,4-5,10-11,13-14H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human neuromedin B receptor transfected in HEK293 cells assessed as inhibition of 1 nM neuromedin B-induced myo-[3H]inositol p...				Bioorg Med Chem Lett 19: 4264-7 (2009) Article DOI: 10.1016/j.bmcl.2009.05.124 BindingDB Entry DOI: 10.7270/Q2C24WG8
					More data for this Ligand-Target Pair
Neuromedin-B receptor (Homo sapiens (Human))	BDBM50295231 ((+)-8'-methyl-11'-(2-(trifluoromethyl)phenyl)-4',5...) Show SMILES Cc1ccc2N=C3CC4(CCCC4)CC(=O)C3C(Nc2c1)c1ccccc1C(F)(F)F |t:5| Show InChI InChI=1S/C25H25F3N2O/c1-15-8-9-18-19(12-15)30-23(16-6-2-3-7-17(16)25(26,27)28)22-20(29-18)13-24(14-21(22)31)10-4-5-11-24/h2-3,6-9,12,22-23,30H,4-5,10-11,13-14H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [125I]-(D-Tyr0)NMB from human neuromedin B receptor transfected in HEK293 cells				Bioorg Med Chem Lett 19: 4264-7 (2009) Article DOI: 10.1016/j.bmcl.2009.05.124 BindingDB Entry DOI: 10.7270/Q2C24WG8
					More data for this Ligand-Target Pair