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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Neuromedin-K receptor (Homo sapiens (Human)) | BDBM242749 (US10030025, Compound 13 | US10836768, Cpd no 13 | ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet  | PC cid PC sid UniChem | US Patent | 40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
BioCryst Pharmaceuticals | Assay Description Human NK-3: The ability of compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist 3H-SB222200 was assessed by an... | Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q2SN0C9W | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Neuromedin-K receptor (Homo sapiens (Human)) | BDBM242749 (US10030025, Compound 13 | US10836768, Cpd no 13 | ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | 40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2348QHC | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Neuromedin-K receptor (Homo sapiens (Human)) | BDBM242749 (US10030025, Compound 13 | US10836768, Cpd no 13 | ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ogeda SA US Patent | Assay Description The affinity of compounds of the invention for the human NK-3 receptor was determined by measuring the ability of compounds of the invention to compe... | US Patent US10836768 (2020) BindingDB Entry DOI: 10.7270/Q2Z03C74 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Neuromedin-K receptor (Homo sapiens (Human)) | BDBM242749 (US10030025, Compound 13 | US10836768, Cpd no 13 | ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 40 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
EUROSCREEN SA US Patent | Assay Description The affinity of compounds of the invention for the human NK-3 receptor was determined by measuring the ability of compounds of the invention to compe... | US Patent US9422299 (2016) BindingDB Entry DOI: 10.7270/Q2GM866C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Neuromedin-K receptor (Homo sapiens (Human)) | BDBM242749 (US10030025, Compound 13 | US10836768, Cpd no 13 | ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 40 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
OGEDA SA US Patent | Assay Description The affinity of compounds of the invention for the human NK-3 receptor was determined by measuring the ability of compounds of the invention to compe... | US Patent US10030025 (2018) BindingDB Entry DOI: 10.7270/Q2B56MSG | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Neuromedin-K receptor (Homo sapiens (Human)) | BDBM242749 (US10030025, Compound 13 | US10836768, Cpd no 13 | ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | 40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details BindingDB Entry DOI: 10.7270/Q2348QHC | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Neuromedin-K receptor (Homo sapiens (Human)) | BDBM242749 (US10030025, Compound 13 | US10836768, Cpd no 13 | ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
OGEDA SA US Patent | Assay Description Changes in intracellular calcium levels are a recognized indicator of G protein-coupled receptor activity. The efficacy of compounds of the invention... | US Patent US10030025 (2018) BindingDB Entry DOI: 10.7270/Q2B56MSG | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Neuromedin-K receptor (Homo sapiens (Human)) | BDBM242749 (US10030025, Compound 13 | US10836768, Cpd no 13 | ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
Ogeda SA US Patent | Assay Description Changes in intracellular calcium levels are a recognized indicator of G protein-coupled receptor activity. The efficacy of compounds of the invention... | US Patent US10836768 (2020) BindingDB Entry DOI: 10.7270/Q2Z03C74 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Neuromedin-K receptor (Homo sapiens (Human)) | BDBM242749 (US10030025, Compound 13 | US10836768, Cpd no 13 | ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
EUROSCREEN SA US Patent | Assay Description Chinese Hamster Ovary recombinant cells expressing the human NK-3 receptor and a construct that encodes the photoprotein apoaequorin were used for th... | US Patent US9422299 (2016) BindingDB Entry DOI: 10.7270/Q2GM866C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
