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Found 1 hit Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-3/beta-4' and Ligand = 'BDBM50508934'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuronal acetylcholine receptor subunit alpha-3/beta-4


(Homo sapiens (Human))		BDBM50508934
PNG
(CHEMBL4463817)
Show SMILES [H][C@@]12CC[C@@]3(C)c4[nH]c5ccccc5c4C[C@@]([H])(NC1(C)C)[C@@]3([H])C2 |r|
Show InChI InChI=1S/C20H26N2/c1-19(2)12-8-9-20(3)15(10-12)17(22-19)11-14-13-6-4-5-7-16(13)21-18(14)20/h4-7,12,15,17,21-22H,8-11H2,1-3H3/t12-,15+,17+,20+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 400n/an/an/an/an/an/a



American University of Health Sciences

Curated by ChEMBL


Assay Description
Antagonist activity at human AChR alpha3beta4 transfected in human HEK293 cells assessed as decrease in epibatidine-induced calcium influx incubated ...

J Nat Prod 82: 1953-1960 (2019)


Article DOI: 10.1021/acs.jnatprod.9b00314
BindingDB Entry DOI: 10.7270/Q2Z89GQP
More data for this
Ligand-Target Pair