Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human)) | BDBM50397933 (CHEMBL2179543) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | 7.30 | -45.8 | n/a | n/a | n/a | n/a | n/a | n/a | 21 |
Targacept, Inc. US Patent | Assay Description The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=... | US Patent US8921410 (2014) BindingDB Entry DOI: 10.7270/Q2QZ28PT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuronal acetylcholine receptor subunit alpha-4 (Rattus norvegicus (Rat)) | BDBM50397933 (CHEMBL2179543) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | 15 | -44.1 | n/a | n/a | n/a | n/a | n/a | n/a | 21 |
Targacept, Inc. US Patent | Assay Description The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=... | US Patent US8921410 (2014) BindingDB Entry DOI: 10.7270/Q2QZ28PT | |||||||||||
More data for this Ligand-Target Pair |