Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat)) | BDBM50081729 (4-{5-[1-Aza-bicyclo[2.2.2]oct-(3Z)-ylidenemethyl]-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >10 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology Curated by ChEMBL | Assay Description The compound was tested for its binding affinity against nicotinic receptor in synaptic membrane fractions from rat cerebral cortices. | Bioorg Med Chem Lett 9: 2795-800 (1999) BindingDB Entry DOI: 10.7270/Q26H4GM1 | |||||||||||
More data for this Ligand-Target Pair |