Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-7' and Ligand = 'BDBM50147161'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM50147161 (CHEMBL3764496) Show SMILES Cl.C1CN2CCC1N(CC2)c1ccc2cccnc2c1 |(5.65,-.25,;-4.72,1.34,;-4.17,2.38,;-5.19,3.67,;-6.16,2.18,;-5.55,.47,;-3.92,,;-2.74,.92,;-2.56,2.65,;-3.5,3.77,;-1.28,.1,;-.01,.99,;1.4,.33,;1.54,-1.2,;2.94,-1.84,;3.08,-3.38,;1.82,-4.27,;.42,-3.62,;.28,-2.09,;-1.12,-1.44,)| Show InChI InChI=1S/C16H19N3.ClH/c1-2-13-3-4-15(12-16(13)17-7-1)19-11-10-18-8-5-14(19)6-9-18;/h1-4,7,12,14H,5-6,8-11H2;1H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.09E+3	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Agonist activity at human alpha7 receptor expressed in mouse Neuro2a cells assessed as induction of intracellular calcium level preincubated with PNU...				Eur J Med Chem 110: 246-58 (2016) Article DOI: 10.1016/j.ejmech.2016.01.025 BindingDB Entry DOI: 10.7270/Q2J1051F
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