Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-7' and Ligand = 'BDBM50149140'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50149140 (3-(Naphthalen-2-ylmethoxy)-1-aza-bicyclo[2.2.2]oct...) Show SMILES C(OC1CN2CCC1CC2)c1ccc2ccccc2c1 |(1.22,.88,;-.11,1.65,;-1.44,.88,;-1.44,-.66,;-2.77,-1.42,;-4.1,-.66,;-4.1,.88,;-2.77,1.66,;-3.38,.49,;-2.33,-.22,;2.57,1.65,;3.88,.86,;5.23,1.63,;5.23,3.17,;6.56,3.94,;6.56,5.48,;5.23,6.27,;3.88,5.48,;3.88,3.94,;2.55,3.17,)| Show InChI InChI=1S/C18H21NO/c1-2-4-17-11-14(5-6-15(17)3-1)13-20-18-12-19-9-7-16(18)8-10-19/h1-6,11,16,18H,7-10,12-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Mitsubishi Pharma Corporation Curated by ChEMBL					Assay Description Binding affinities of the compound for the alpha 7 nicotinic acetylcholine receptor was determined in PC12 cells				Bioorg Med Chem Lett 14: 3781-4 (2004) Article DOI: 10.1016/j.bmcl.2004.04.091 BindingDB Entry DOI: 10.7270/Q2X066G1
					More data for this Ligand-Target Pair