Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-7' and Ligand = 'BDBM50161255'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM50161255 (CHEMBL3786288) Show SMILES Cl.Brc1ccccc1C(=O)c1cc(C(=O)N[C@H]2CN3CCC2CC3)c2ccccn12 |r,wD:16.15,(9.33,-.95,;3.41,5.4,;4.23,4.48,;5.74,4.79,;6.76,3.64,;6.28,2.18,;4.77,1.86,;3.75,3.01,;2.24,2.7,;1.42,3.61,;1.76,1.24,;2.66,.02,;1.76,-1.24,;2.24,-2.7,;1.42,-3.62,;3.75,-3.01,;4.24,-4.47,;3.14,-5.65,;3.64,-7.18,;5.22,-7.52,;6.32,-6.32,;5.83,-4.77,;4.63,-5.27,;5,-6.47,;.3,-.77,;-1.03,-1.55,;-2.38,-.77,;-2.38,.77,;-1.03,1.55,;.3,.77,)| Show InChI InChI=1S/C23H22BrN3O2.ClH/c24-18-6-2-1-5-16(18)22(28)21-13-17(20-7-3-4-10-27(20)21)23(29)25-19-14-26-11-8-15(19)9-12-26;/h1-7,10,13,15,19H,8-9,11-12,14H2,(H,25,29);1H/t19-;/m0./s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Agonist activity at human alpha7 nAChR expressed in xenopus oocytes preincubated for 10 mins followed by acetylcholine addition by patch clamp electr...				Eur J Med Chem 115: 94-108 (2016) Article DOI: 10.1016/j.ejmech.2016.03.016 BindingDB Entry DOI: 10.7270/Q2W37Z6N
					More data for this Ligand-Target Pair