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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-7' and Ligand = 'BDBM50173943'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuronal acetylcholine receptor subunit alpha-7


(Homo sapiens (Human))		BDBM50173943
PNG
(5-Phenyl-thiophene-2-carboxylic acid (1-aza-bicycl...)
Show SMILES O=C(NC1CN2CCC1CC2)c1ccc(s1)-c1ccccc1 |THB:2:3:9.10:7.6,(5.48,-.12,;4.92,-1.57,;3.39,-1.79,;2.44,-.57,;2.15,.83,;.8,1.44,;.87,3.08,;1.32,1.96,;1.06,.07,;-.48,-.59,;-.68,.79,;5.88,-2.77,;5.46,-4.26,;6.74,-5.12,;7.95,-4.16,;7.41,-2.71,;9.43,-4.58,;9.43,-6.11,;10.76,-6.88,;12.1,-6.13,;12.1,-4.58,;10.77,-3.81,)|
Show InChI InChI=1S/C18H20N2OS/c21-18(19-15-12-20-10-8-13(15)9-11-20)17-7-6-16(22-17)14-4-2-1-3-5-14/h1-7,13,15H,8-12H2,(H,19,21)
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KEGG

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PC cid
PC sid
UniChem

Similars
Article
PubMed
 3.40n/an/an/an/an/an/an/an/a



Eli Lilly and Company Ltd.

Curated by ChEMBL


Assay Description
Binding affinity towards human nicotinic acetylcholine receptor alpha 7 expressed in GH4C1 cell using [3H]methyllycaconitine

Bioorg Med Chem Lett 15: 4727-30 (2005)


Article DOI: 10.1016/j.bmcl.2005.07.070
BindingDB Entry DOI: 10.7270/Q28K79W0
More data for this
Ligand-Target Pair